Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis.
Hurrell T, Kastrinou-Lampou V, Fardellas A, Hendriks DFG, Nordling Å, Johansson I, Baze A, Parmentier C, Richert L, Ingelman-Sundberg M.
Hurrell T, et al.
Cells. 2020 Apr 14;9(4):964. doi: 10.3390/cells9040964.
Cells. 2020.
PMID: 32295224
Free PMC article.
Non-alcoholic steatohepatitis (NASH) is a progressive disease and underlies the advancement to liver fibrosis, cirrhosis, and hepatocellular carcinoma, for which there are no FDA-approved drug therapies. ...Co-culture spheroids displayed stable expression of hepatocyte mar …
Non-alcoholic steatohepatitis (NASH) is a progressive disease and underlies the advancement to liver fibrosis, cirrhosis, and hepatoc …